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Hippocampal Gα(q/11) but not Gα(o)-coupled receptors are altered in aging
Normal aging may limit the signaling efficacy of certain GPCRs by disturbing the function of specific Gα-subunits and leading to deficient modulation of intracellular functions that subserve synaptic plasticity, learning and memory. Evidence suggests that Gα(q/11) is more sensitive to the effects of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705722/ https://ncbi.nlm.nih.gov/pubmed/23347951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.01.009 |
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