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Interaction of Gα(12) with Gα(13) and Gα(q) signaling pathways

The G(12) subfamily of heterotrimeric G-proteins consists of two members, G(12) and G(13). Gene-targeting studies have revealed a role for G(13) in blood vessel development. Mice lacking the α subunit of G(13) die around embryonic day 10 as the result of an angiogenic defect. On the other hand, the...

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Bibliografski detalji
Glavni autori: Gu, Jennifer L., Müller, Stefan, Mancino, Valeria, Offermanns, Stefan, Simon, Melvin I.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC123144/
https://ncbi.nlm.nih.gov/pubmed/12077299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102291599
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