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IL-2 signaling prevents T cell anergy by inhibiting the expression of anergy inducing genes

T cell responses are determined by the environment in which antigen is encountered. In the absence of proper costimulation, anergizing stimuli induce the activation of a specific program of gene expression. Proteins encoded by these genes impose a state of functional unresponsiveness in anergic T ce...

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Bibliografski detalji
Glavni autori: Dure, Myrianne, Macian, Fernando
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667138/
https://ncbi.nlm.nih.gov/pubmed/18990450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.09.029
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