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Silencing of the Il2 gene transcription is regulated by epigenetic changes in anergic T cells
Anergy is induced in T cells as a consequence of a partial or suboptimal stimulation. Anergic T cells become unresponsive and fail to proliferate and produce cytokines. We had previously shown that in anergic CD4+ T cells, Ikaros participates in the transcriptional repression of the Il2 gene by recr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681531/ https://ncbi.nlm.nih.gov/pubmed/22684523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142307 |
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