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Interleukin 2 gene transcription is regulated by Ikaros-induced changes in histone acetylation in anergic T cells
In T cells anergy may be evoked by an unbalanced stimulation of the T-cell receptor in the absence of costimulation. Anergic T cells are unresponsive to new antigen receptor engagement and do not produce interleukin 2. We present evidence that anergizing stimuli induce changes in histone acetylation...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852212/ https://ncbi.nlm.nih.gov/pubmed/17148585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-037754 |
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