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Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cells
T cell receptor engagement in the absence of costimulation induces the calcium-dependent upregulation of the expression of a specific set of genes, which leads to the establishment of T cell anergy. Caspase 3 is one of the genes activated during anergy induction. We show that upregulation of caspase...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630799/ https://ncbi.nlm.nih.gov/pubmed/18701083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.06.010 |
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