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IL-2 signaling prevents T cell anergy by inhibiting the expression of anergy inducing genes
T cell responses are determined by the environment in which antigen is encountered. In the absence of proper costimulation, anergizing stimuli induce the activation of a specific program of gene expression. Proteins encoded by these genes impose a state of functional unresponsiveness in anergic T ce...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667138/ https://ncbi.nlm.nih.gov/pubmed/18990450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.09.029 |
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