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Tle4 Regulates Epigenetic Silencing of Gamma Interferon Expression during Effector T Helper Cell Tolerance

In response to suboptimal activation, T cells become hyporesponsive, with a severely reduced capacity to proliferate and produce cytokines upon reencounter with antigen. Chromatin analysis of T cells made tolerant by use of different in vitro and in vivo approaches reveals that the expression of gam...

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Autori principali: Bandyopadhyay, Sanmay, Valdor, Rut, Macian, Fernando
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911291/
https://ncbi.nlm.nih.gov/pubmed/24190972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00902-13
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