Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ production

IL-23/IL-17-induced neutrophil recruitment plays a pivotal role in rheumatoid arthritis (RA). However, the mechanism of the neutrophil recruitment is obscure. Here we report that prostaglandin enhances the IL-23/IL-17-induced neutrophil migration in a murine model of RA by inhibiting IL-12 and IFN γ...

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Библиографические подробности
Главные авторы: Lemos, Henrique P., Grespan, Renata, Vieira, Silvio M., Cunha, Thiago M., Verri, Waldiceu A., Fernandes, Karla S. S., Souto, Fabricio O., McInnes, Iain B., Ferreira, Sergio H., Liew, Foo Y., Cunha, Fernando Q.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667068/
https://ncbi.nlm.nih.gov/pubmed/19289819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812782106
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