IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E(2)

BACKGROUND AND PURPOSE: IL-33 signals through ST2 receptors and induces adaptive and innate inflammation. IL-33/ST2 is involved in adaptive inflammation-induced pain. Here, we have investigated the contribution of IL-33/ST2-triggered mechanisms to carrageenin-induced innate inflammation. EXPERIMENTA...

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Detalhes bibliográficos
Main Authors: Zarpelon, AC, Cunha, TM, Alves-Filho, JC, Pinto, LG, Ferreira, SH, McInnes, IB, Xu, D, Liew, FY, Cunha, FQ, Verri, WA
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632241/
https://ncbi.nlm.nih.gov/pubmed/23347081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12110
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