Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ production

IL-23/IL-17-induced neutrophil recruitment plays a pivotal role in rheumatoid arthritis (RA). However, the mechanism of the neutrophil recruitment is obscure. Here we report that prostaglandin enhances the IL-23/IL-17-induced neutrophil migration in a murine model of RA by inhibiting IL-12 and IFN γ...

詳細記述

保存先:
書誌詳細
主要な著者: Lemos, Henrique P., Grespan, Renata, Vieira, Silvio M., Cunha, Thiago M., Verri, Waldiceu A., Fernandes, Karla S. S., Souto, Fabricio O., McInnes, Iain B., Ferreira, Sergio H., Liew, Foo Y., Cunha, Fernando Q.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667068/
https://ncbi.nlm.nih.gov/pubmed/19289819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812782106
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