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Neurokinin 1 Receptor Mediates Membrane Blebbing in HEK293 Cells through a Rho/Rho-associated Coiled-coil Kinase-dependent Mechanism

We have investigated the effect of neurokinin 1 receptor (NK1R) agonists on HEK293 cells transfected with the NK1R receptor. The NK1R receptor mediates dramatic shape changes that include contractions of the membrane cortex resulting in membrane bleb formation. We have found that the cell shape chan...

詳細記述

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書誌詳細
主要な著者: Meshki, John, Douglas, Steven D., Lai, Jian-Ping, Schwartz, Lynnae, Kilpatrick, Laurie E., Tuluc, Florin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666580/
https://ncbi.nlm.nih.gov/pubmed/19179340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808825200
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