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Neurokinin 1 Receptor Mediates Membrane Blebbing in HEK293 Cells through a Rho/Rho-associated Coiled-coil Kinase-dependent Mechanism

We have investigated the effect of neurokinin 1 receptor (NK1R) agonists on HEK293 cells transfected with the NK1R receptor. The NK1R receptor mediates dramatic shape changes that include contractions of the membrane cortex resulting in membrane bleb formation. We have found that the cell shape chan...

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Detalhes bibliográficos
Main Authors: Meshki, John, Douglas, Steven D., Lai, Jian-Ping, Schwartz, Lynnae, Kilpatrick, Laurie E., Tuluc, Florin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666580/
https://ncbi.nlm.nih.gov/pubmed/19179340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808825200
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