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Neurokinin 1 Receptor Mediates Membrane Blebbing in HEK293 Cells through a Rho/Rho-associated Coiled-coil Kinase-dependent Mechanism

We have investigated the effect of neurokinin 1 receptor (NK1R) agonists on HEK293 cells transfected with the NK1R receptor. The NK1R receptor mediates dramatic shape changes that include contractions of the membrane cortex resulting in membrane bleb formation. We have found that the cell shape chan...

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Библиографические подробности
Главные авторы: Meshki, John, Douglas, Steven D., Lai, Jian-Ping, Schwartz, Lynnae, Kilpatrick, Laurie E., Tuluc, Florin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666580/
https://ncbi.nlm.nih.gov/pubmed/19179340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808825200
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