Substance P inhibits natural killer cell cytotoxicity through the neurokinin-1 receptor

SP is a potent neuroimmunomodulator that functions through ligating members of the neurokinin receptor family, one of which, NK1R, is widely expressed in immune cells. As in humans, circulating SP levels are increased in pathologic states associated with impairment of NK cell functions, such as depr...

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Detalhes bibliográficos
Main Authors: Monaco-Shawver, Linda, Schwartz, Lynnae, Tuluc, Florin, Guo, Chang-Jiang, Lai, Jian Ping, Gunnam, Satya M., Kilpatrick, Laurie E., Banerjee, Pinaki P., Douglas, Steven D., Orange, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2011
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004520/
https://ncbi.nlm.nih.gov/pubmed/20940324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0410200
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