Substance P inhibits natural killer cell cytotoxicity through the neurokinin-1 receptor

SP is a potent neuroimmunomodulator that functions through ligating members of the neurokinin receptor family, one of which, NK1R, is widely expressed in immune cells. As in humans, circulating SP levels are increased in pathologic states associated with impairment of NK cell functions, such as depr...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Monaco-Shawver, Linda, Schwartz, Lynnae, Tuluc, Florin, Guo, Chang-Jiang, Lai, Jian Ping, Gunnam, Satya M., Kilpatrick, Laurie E., Banerjee, Pinaki P., Douglas, Steven D., Orange, Jordan S.
التنسيق: Artigo
اللغة:Inglês
منشور في: Society for Leukocyte Biology 2011
الموضوعات:
Inflammation, Extracellular Mediators, & Effector Molecules
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004520/
https://ncbi.nlm.nih.gov/pubmed/20940324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0410200
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