GLI1 Is a Direct Transcriptional Target of EWS-FLI1 Oncoprotein

Ewing sarcoma family of tumors (ESFT) is an undifferentiated neoplasm of the bone and soft tissue. ESFT is characterized by a specific chromosomal translocation occurring between chromosome 22 and (in most cases) chromosome 11, which generates an aberrant transcription factor, EWS-FLI1. The function...

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Autori principali: Beauchamp, Elspeth, Bulut, Gulay, Abaan, Ogan, Chen, Kevin, Merchant, Akil, Matsui, William, Endo, Yoshimi, Rubin, Jeffrey S., Toretsky, Jeffrey, Üren, Aykut
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Mechanisms of Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666556/
https://ncbi.nlm.nih.gov/pubmed/19189974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806233200
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