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mtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints

Multiple human mutational landscapes of normal and cancer conditions are currently available. However, while the unique mutational patterns of tumors have been extensively studied, little attention has been paid to similarities between malignant and normal conditions. Here we compared the pattern of...

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Bibliografske podrobnosti
Main Authors: Zhidkov, Ilia, Livneh, Erez A., Rubin, Eitan, Mishmar, Dan
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665776/
https://ncbi.nlm.nih.gov/pubmed/19211544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.086462.108
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