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mtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints

Multiple human mutational landscapes of normal and cancer conditions are currently available. However, while the unique mutational patterns of tumors have been extensively studied, little attention has been paid to similarities between malignant and normal conditions. Here we compared the pattern of...

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Detalhes bibliográficos
Main Authors: Zhidkov, Ilia, Livneh, Erez A., Rubin, Eitan, Mishmar, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665776/
https://ncbi.nlm.nih.gov/pubmed/19211544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.086462.108
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