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Mitochondrial DNA heteroplasmy in diabetes and normal adults: role of acquired and inherited mutational patterns in twins

Heteroplasmy, the mixture of mitochondrial genomes (mtDNA), varies among individuals and cells. Heteroplasmy levels alter the penetrance of pathological mtDNA mutations, and the susceptibility to age-related diseases such as Parkinson's disease. Although mitochondrial dysfunction occurs in age-...

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Autors principals: Avital, Gal, Buchshtav, Mor, Zhidkov, Ilia, Tuval (Feder), Jeanette, Dadon, Sarah, Rubin, Eitan, Glass, Dan, Spector, Timothy D., Mishmar, Dan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441121/
https://ncbi.nlm.nih.gov/pubmed/22736028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds245
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