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Very Low-Level Heteroplasmy mtDNA Variations Are Inherited in Humans

Little is known about the inheritance of very low heteroplasmy mitochondria DNA variations. Even with the development of new next-generation sequencing methods, the practical lower limit of measured heteroplasmy is still about 1% due to the inherent noise level of the sequencing. In this study, we s...

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Detalhes bibliográficos
Main Authors: Guo, Yan, Li, Chung-I, Sheng, Quanhu, Winther, Jeanette F., Cai, Qiuyin, Boice, John D., Shyr, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149221/
https://ncbi.nlm.nih.gov/pubmed/24377867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2013.10.003
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