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The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events
Accumulating evidence suggests that neurons prone to degeneration in Alzheimer's Disease (AD) exhibit evidence of re-entry into an aberrant mitotic cell cycle. Our laboratory recently demonstrated that, in a genomic amyloid precursor protein (APP) mouse model of AD (R1.40), neuronal cell cycle...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663563/ https://ncbi.nlm.nih.gov/pubmed/19291319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-4-14 |
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