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The Critical Contribution of TGF-β to the Induction of Foxp3 Expression and Treg Function
Stimulation of mouse CD4(+) T cells in the presence of TGF-β results in the expression of Foxp3 and induction of Treg function. Stimulation of human CD4(+) T cells under similar conditions results in the expression of Foxp3, but the cells lack regulatory cell function. TGF-β expressed on the surface...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662375/ https://ncbi.nlm.nih.gov/pubmed/18395859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200738111 |
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