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IL-2 Controls the Stability of Foxp3 expression in TGF-β-induced Foxp3(+) T cells in vivo
Stimulation of naïve mouse CD4(+)Foxp3(−) T cells in the presence of TGF-β results in the induction of Foxp3 expression and T suppressor function. However, Foxp3 expression in these induced T regulatory cells (iTreg) is unstable raising the possibility that iTreg would not be useful for treatment of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098943/ https://ncbi.nlm.nih.gov/pubmed/21525380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100061 |
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