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Oligodeoxynucleotides stabilize Helios-expressing Foxp3(+) human T regulatory cells during in vitro expansion

Foxp3(+) regulatory T cells (Tregs) maintain self-tolerance and adoptive therapy, and using Foxp3(+) Tregs has been proposed as treatment for autoimmune diseases. The clinical use of Tregs will require large numbers of cells and methods for in vitro expansion of Tregs are being developed. Foxp3(+) T...

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Hlavní autoři: Kim, Yong Chan, Bhairavabhotla, Ravikiran, Yoon, Jeongheon, Golding, Amit, Thornton, Angela M., Tran, Dat Q., Shevach, Ethan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327459/
https://ncbi.nlm.nih.gov/pubmed/22294730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377895
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