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SAMHD1 post-transcriptionally controls the expression of Foxp3 and Helios in Human T regulatory Cells

Clinical application of antigen-specific T regulatory cells (Tregs) offers promise for the treatment of undesirable immune diseases. To achieve this goal, long-term expansion of Tregs is required to obtain sufficient numbers of cells. However, human Tregs are not stable ex vivo. Therefore, we previo...

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Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Kim, Yong Chan, Kim, Kee Kwang, Yoon, Jeongheon, Scott, David W., Shevach, Ethan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125212/
https://ncbi.nlm.nih.gov/pubmed/30104243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800613
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