Načítá se...
Intramembrane Proteolysis by γ-Secretase
γ-Secretase mediates the final proteolytic cleavage, which liberates amyloid β-peptide (Aβ), the major component of senile plaques in the brains of Alzheimer disease patients. Therefore, γ-secretase is a prime target for Aβ-lowering therapeutic strategies. γ-Secretase is a protein complex composed o...
Uloženo v:
| Hlavní autoři: | , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2008
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662049/ https://ncbi.nlm.nih.gov/pubmed/18650432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800010200 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|