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Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

Children with Down syndrome (DS) show a spectrum of clinical anomalies, including cognitive impairment, cardiac malformations, and craniofacial dysmorphy. Moreover, hematologists have also noted that these children commonly show macrocytosis, abnormal platelet counts, and an increased incidence of t...

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Detalhes bibliográficos
Main Authors: Malinge, Sébastien, Izraeli, Shai, Crispino, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661853/
https://ncbi.nlm.nih.gov/pubmed/19139078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-163501
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