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Down syndrome and leukemia: insights into leukemogenesis and translational targets

Children with Down syndrome (DS) have a significantly increased risk of childhood leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia (DS-ALL). A pre-leukemia, called transient myeloproliferative disorder (TMD), characterised by a GATA binding protein 1 (G...

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Detalhes bibliográficos
Publicado no:Transl Pediatr
Main Authors: Mateos, Marion K., Barbaric, Draga, Byatt, Sally-Anne, Sutton, Rosemary, Marshall, Glenn M.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729084/
https://ncbi.nlm.nih.gov/pubmed/26835364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2224-4336.2015.03.03
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