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The Biology, Pathogenesis and Clinical Aspects of Acute Lymphoblastic Leukemia in Children with Down Syndrome
Children with Down syndrome (DS) are at a 20-fold increased risk for acute lymphoblastic leukemia (DS-ALL). Although the etiology of this higher risk of developing leukemia remains largely unclear, the recent identification of CRLF2 and JAK2 mutations and study of the effect of trisomy of Hmgn1 and...
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| Publicado no: | Leukemia |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5434972/ https://ncbi.nlm.nih.gov/pubmed/27285583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.164 |
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