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Prevalence and clinical correlates of JAK2 mutations in Down syndrome acute lymphoblastic leukemia
Recurrent, prognostically significant chromosomal abnormalities occur in approximately 75% of pediatric acute lymphoblastic leukemia (ALL), but only infrequently in children with Down syndrome (DS) and ALL. Recently, novel somatic activating mutations in Janus kinase 2 (JAK2) were reported in 18% of...
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Asıl Yazarlar: | , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2008
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724897/ https://ncbi.nlm.nih.gov/pubmed/19120350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2008.07552.x |
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