REARRANGEMENT OF CRLF2 IN B-PROGENITOR AND DOWN SYNDROME ASSOCIATED ACUTE LYMPHOBLASTIC LEUKEMIA

Aneuploidy and translocations are hallmarks of B-progenitor acute lymphoblastic leukemia (ALL), but many patients lack a recurring chromosomal alteration. Here we report a recurring interstitial deletion of the pseudoautosomal region 1 of chromosomes X and Y in B-progenitor ALL that juxtaposes the f...

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Hoofdauteurs: Mullighan, Charles G., Collins-Underwood, J Racquel, Phillips, Letha A.A., Loudin, Michael L., Liu, Wei, Zhang, Jinghui, Ma, Jing, Coustan-Smith, Elaine, Harvey, Richard C., Willman, Cheryl L., Mikhail, Fady M., Meyer, Julia, Carroll, Andrew J., Williams, Richard T., Cheng, Jinjun, Heerema, Nyla A., Basso, Giuseppe, Pession, Andrea, Pui, Ching-Hon, Raimondi, Susana C., Hunger, Stephen P., Downing, James R., Carroll, William L., Rabin, Karen R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783810/
https://ncbi.nlm.nih.gov/pubmed/19838194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.469
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