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Differential in vitro cytotoxicity does not explain increased host toxicities from chemotherapy in Down syndrome acute lymphoblastic leukemia

Treatment-related toxicities such as mucositis and infections are both more frequent and more severe in children with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) compared to non-DS ALL. Altered methotrexate pharmacodynamics play a role, but severe toxicities also occur in treatment cou...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Valle, Mariela, Plon, Sharon E., Rabin, Karen R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637345/
https://ncbi.nlm.nih.gov/pubmed/18718659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2008.07.011
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