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Increased RNAi is related to intracellular release of siRNA via a covalently attached signal peptide
In the last decade short interfering RNA (siRNA) became an important means for functional genomics and the development of gene-specific drugs. However, major technical hurdles in the application of siRNA include its cellular delivery followed by its intracellular trafficking and its release in order...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661840/ https://ncbi.nlm.nih.gov/pubmed/19228587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1305209 |
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