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Cell stress is related to re-localization of Argonaute 2 and to decreased RNA interference in human cells

Various kinds of stress on human cells induce the formation of endogenous stress granules (SGs). Human Argonaute 2 (hAgo2), the catalytic core component of the RNA-induced silencing complex (RISC), can be recruited to SGs as well as P-bodies (PBs) indicating that the dynamic intracellular distributi...

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Detalhes bibliográficos
Main Authors: Detzer, Anke, Engel, Christina, Wünsche, Winfried, Sczakiel, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074141/
https://ncbi.nlm.nih.gov/pubmed/21148147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1216
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