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A hexanucleotide selected for increased cellular uptake in cis contains a highly active CpG-motif in human B cells and primary peripheral blood mononuclear cells
The relationship between immunostimulation of human B cells by cytosine–phosphate–guanosine (CpG) -containing oligonucleotides and their physical cellular uptake is of mechanistic interest and a prerequisite for rational improvements of the therapeutic potential of CpG-harbouring oligonucleotides. H...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265851/ https://ncbi.nlm.nih.gov/pubmed/17137465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02497.x |
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