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Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study
The goal of this study was to evaluate the time course of metabolic changes in leukaemia cells treated with the Bcr-Abl tyrosine kinase inhibitor imatinib. Human Bcr-Abl(+) K562 cells were incubated with imatinib in a dose-escalating manner (starting at 0.1 μM with a weekly increase of 0.1 μM imatin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661771/ https://ncbi.nlm.nih.gov/pubmed/19259085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604946 |
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