Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study

The goal of this study was to evaluate the time course of metabolic changes in leukaemia cells treated with the Bcr-Abl tyrosine kinase inhibitor imatinib. Human Bcr-Abl(+) K562 cells were incubated with imatinib in a dose-escalating manner (starting at 0.1 μM with a weekly increase of 0.1 μM imatin...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Klawitter, J, Anderson, N, Christians, U, Leibfritz, D, Eckhardt, S G, Serkova, N J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
Teme:
Translational Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661771/
https://ncbi.nlm.nih.gov/pubmed/19259085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604946
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki