Metabolic characteristics of imatinib resistance in chronic myeloid leukaemia cells

BACKGROUND AND PURPOSE: Early detection of resistance development is crucial for imatinib-based treatment in chronic myeloid leukaemia (CML) patients. We aimed to distinguish metabolic markers of cell resistance to imatinib. EXPERIMENTAL APPROACH: Two human imatinib-sensitive CML cell lines: LAMA84-...

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Detalhes bibliográficos
Main Authors: Klawitter, Jelena, Kominsky, Douglas J, Brown, Jaimi L, Klawitter, Jost, Christians, Uwe, Leibfritz, Dieter, Melo, Junia V, Eckhardt, S Gail, Serkova, Natalie J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757699/
https://ncbi.nlm.nih.gov/pubmed/19663881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00345.x
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