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Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line
Depending on the species and the developmental stage of B cells, activation-induced cytidine deaminase (AID) triggers immunoglobulin (Ig) gene diversification by gene conversion, hypermutation or switch recombination. The bursal B cell line DT40 usually diversifies its rearranged Ig light chain (IgL...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660921/ https://ncbi.nlm.nih.gov/pubmed/19008193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0202 |
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