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Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line

Depending on the species and the developmental stage of B cells, activation-induced cytidine deaminase (AID) triggers immunoglobulin (Ig) gene diversification by gene conversion, hypermutation or switch recombination. The bursal B cell line DT40 usually diversifies its rearranged Ig light chain (IgL...

詳細記述

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書誌詳細
主要な著者: Arakawa, Hiroshi, Buerstedde, Jean-Marie
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660921/
https://ncbi.nlm.nih.gov/pubmed/19008193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0202
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