Chemical tools selectively target components of the PKA system

BACKGROUND: In the eukaryotic cell the cAMP-dependent protein kinase (PKA) is a key enzyme in signal transduction and represents the main target of the second messenger cAMP. Here we describe the design, synthesis and characterisation of specifically tailored cAMP analogs which can be utilised as a...

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Detalhes bibliográficos
Main Authors: Bertinetti, Daniela, Schweinsberg, Sonja, Hanke, Susanne E, Schwede, Frank, Bertinetti, Oliver, Drewianka, Stephan, Genieser, Hans-Gottfried, Herberg, Friedrich W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660902/
https://ncbi.nlm.nih.gov/pubmed/19216744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-9-3
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