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New cGMP analogues restrain proliferation and migration of melanoma cells

Melanoma is one of the most aggressive cancers and displays high resistance to conventional chemotherapy underlining the need for new therapeutic strategies. The cGMP/PKG signaling pathway was detected in melanoma cells and shown to reduce migration, proliferation and to increase apoptosis in differ...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vighi, Eleonora, Rentsch, Andreas, Henning, Philipp, Comitato, Antonella, Hoffmann, Dorit, Bertinetti, Daniela, Bertolotti, Evelina, Schwede, Frank, Herberg, Friedrich W., Genieser, Hans-Gottfried, Marigo, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797051/
https://ncbi.nlm.nih.gov/pubmed/29435180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23685
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