Chemical tools selectively target components of the PKA system

BACKGROUND: In the eukaryotic cell the cAMP-dependent protein kinase (PKA) is a key enzyme in signal transduction and represents the main target of the second messenger cAMP. Here we describe the design, synthesis and characterisation of specifically tailored cAMP analogs which can be utilised as a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bertinetti, Daniela, Schweinsberg, Sonja, Hanke, Susanne E, Schwede, Frank, Bertinetti, Oliver, Drewianka, Stephan, Genieser, Hans-Gottfried, Herberg, Friedrich W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2009
Gaiak:
Methodology Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660902/
https://ncbi.nlm.nih.gov/pubmed/19216744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-9-3
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