Ste20-Related Proline/Alanine-Rich Kinase (SPAK) Regulated Transcriptionally by Hyperosmolarity Is Involved in Intestinal Barrier Function

The Ste20-related protein proline/alanine-rich kinase (SPAK) plays important roles in cellular functions such as cell differentiation and regulation of chloride transport, but its roles in pathogenesis of intestinal inflammation remain largely unknown. Here we report significantly increased SPAK exp...

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Detalhes bibliográficos
Main Authors: Yan, Yutao, Dalmasso, Guillaume, Thi Thu Nguyen, Hang, Obertone, Tracy S., Sitaraman, Shanthi V., Merlin, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660421/
https://ncbi.nlm.nih.gov/pubmed/19343169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005049
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