Ste20-Related Proline/Alanine-Rich Kinase (SPAK) Regulated Transcriptionally by Hyperosmolarity Is Involved in Intestinal Barrier Function

The Ste20-related protein proline/alanine-rich kinase (SPAK) plays important roles in cellular functions such as cell differentiation and regulation of chloride transport, but its roles in pathogenesis of intestinal inflammation remain largely unknown. Here we report significantly increased SPAK exp...

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Main Authors: Yan, Yutao, Dalmasso, Guillaume, Thi Thu Nguyen, Hang, Obertone, Tracy S., Sitaraman, Shanthi V., Merlin, Didier
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660421/
https://ncbi.nlm.nih.gov/pubmed/19343169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005049
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