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Ste20-Related Proline/Alanine-Rich Kinase (SPAK) Regulated Transcriptionally by Hyperosmolarity Is Involved in Intestinal Barrier Function

The Ste20-related protein proline/alanine-rich kinase (SPAK) plays important roles in cellular functions such as cell differentiation and regulation of chloride transport, but its roles in pathogenesis of intestinal inflammation remain largely unknown. Here we report significantly increased SPAK exp...

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Bibliografiske detaljer
Main Authors: Yan, Yutao, Dalmasso, Guillaume, Thi Thu Nguyen, Hang, Obertone, Tracy S., Sitaraman, Shanthi V., Merlin, Didier
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660421/
https://ncbi.nlm.nih.gov/pubmed/19343169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005049
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