Nuclear Factor-κB Is a Critical Mediator of Ste20-Like Proline-/Alanine-Rich Kinase Regulation in Intestinal Inflammation

Inflammatory bowel disease (IBD) is thought to result from commensal flora, aberrant cellular stress, and genetic factors. Here we show that the expression of colonic Ste20-like proline-/alanine-rich kinase (SPAK) that lacks a PAPA box and an F-α helix loop is increased in patients with IBD. The sam...

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Main Authors: Yan, Yutao, Dalmasso, Guillaume, Nguyen, Hang Thi Thu, Obertone, Tracy S., Charrier-Hisamuddin, Laetitia, Sitaraman, Shanthi V., Merlin, Didier
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2008
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543070/
https://ncbi.nlm.nih.gov/pubmed/18787102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080339
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