Nuclear Factor-κB Is a Critical Mediator of Ste20-Like Proline-/Alanine-Rich Kinase Regulation in Intestinal Inflammation

Inflammatory bowel disease (IBD) is thought to result from commensal flora, aberrant cellular stress, and genetic factors. Here we show that the expression of colonic Ste20-like proline-/alanine-rich kinase (SPAK) that lacks a PAPA box and an F-α helix loop is increased in patients with IBD. The sam...

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Autors principals: Yan, Yutao, Dalmasso, Guillaume, Nguyen, Hang Thi Thu, Obertone, Tracy S., Charrier-Hisamuddin, Laetitia, Sitaraman, Shanthi V., Merlin, Didier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2008
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543070/
https://ncbi.nlm.nih.gov/pubmed/18787102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080339
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