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Modulation of PKCδ signaling alters the shear stress-mediated increases in endothelial nitric oxide synthase transcription: role of STAT3

We have previously shown that the regulation of endothelial nitric oxide synthase (eNOS) in endothelial cells isolated from fetal lamb under static conditions is positively regulated by PKCδ. In this study, we explore the role of PKCδ in regulating shear-induced upregulation of eNOS. We found that s...

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Detalhes bibliográficos
Main Authors: Sud, Neetu, Kumar, Sanjiv, Wedgwood, Stephen, Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660219/
https://ncbi.nlm.nih.gov/pubmed/19118090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90534.2008
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