Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

Arsenic is a well-known human skin carcinogen but the underlying mechanisms of carcinogenesis are unclear. Transcription factor Nrf2-mediated antioxidant response represents a critical cellular defense mechanism, and emerging data suggest that constitutive activation of Nrf2 contributes to malignant...

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Bibliografiske detaljer
Main Authors: Pi, Jingbo, Diwan, Bhalchandra A., Sun, Yang, Liu, Jie, Qu, Wei, He, Yuying, Styblo, Miroslav, Waalkes, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658531/
https://ncbi.nlm.nih.gov/pubmed/18572023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.05.020
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