Aberrant Cytokeratin Expression During Arsenic-induced Acquired Malignant Phenotype in Human HaCaT Keratinocytes Consistent with Epidermal Carcinogenesis

Inorganic arsenic is a known human skin carcinogen. Chronic arsenic exposure results in various human skin lesions, including hyperkeratosis and squamous cell carcinoma (SCC), both characterized by distorted cytokeratin (CK) production. Prior work shows the human skin keratinocyte HaCaT cell line, w...

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Main Authors: Sun, Yang, Pi, Jingbo, Wang, Xueqian, Tokar, Erik J., Liu, Jie, Waalkes, Michael P.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747077/
https://ncbi.nlm.nih.gov/pubmed/19524636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2009.06.003
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